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The principal cytochrome P450 isoenzyme included seems for being CYP2E1, with CYP1A2 and CYP3A4 as additional pathways. Close to 85% of the oral dose appears while in the urine within just 24 several hours of administration, most because the glucuronide conjugate, with compact quantities of other conjugates and unchanged drug [see OVERDOSAGE] for t